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Antisense-oligonucleotides for the treatment of immuno-suppressive effects of transforming growth factor-beta (TGF-beta)

机译:反义寡核苷酸用于治疗转化生长因子-beta(TGF-beta)的免疫抑制作用

摘要

Antisense-oligonucleotides or effective derivatives thereof hybridizing with an area of a gene coding for transforming growth factor-β (TGF-β) comprising the following nucleic acid sequences identified in the sequence listing under SEQ ID NO. 1-56 and 137 or comprising the following nucleic acid sequences identified in the sequence listing under SEQ ID NO. 57 to 136 each of the nucleic acids having a DNA- or RNA-type structure.
机译:与编码转化生长因子-β(TGF-β)的基因的区域杂交的反义-寡核苷酸或其有效衍生物,所述基因包含在SEQ ID NO.1的序列表中鉴定的以下核酸序列。 1-56和137或包含以下核酸序列,所述核酸序列在SEQ ID NO.1的序列表中鉴定。参照图57至136,每个具有DNA或RNA型结构的核酸。

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