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Pathogen Detection Using Coherent Anti-Stokes Raman Scattering Microscopy
Pathogen Detection Using Coherent Anti-Stokes Raman Scattering Microscopy
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机译:相干反斯托克斯拉曼散射显微镜检测病原体
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摘要
The invention provides a system and method for automatic real-time monitoring for the presence of a pathogen in water using coherent anti-stokes Raman scattering (CARS) microscopy. Water sample trapped in a trapping medium is provided to a CARS imager. CARS images are provided to a processor for automatic analyzing for the presence of image artifacts having pre-determined features characteristic to the pathogen. If a match is found, a CARS spectrum is taken and compared to a stored library of reference pathogen-specific spectra for pathogen identification. The system enables automatic pathogen detection in flowing water in real time.
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