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Dispensing device, dispensing method and method of detecting defective discharge of solution containing biological sample

机译:分配装置,分配方法以及检测含有生物样品的溶液的不良排出的方法

摘要

Proposed is dispensing technology capable of reliably spotting a biological sample on a solid phase. A head chip applies a voltage pulse between a diaphragm and separate electrodes based on a drive control signal output from a head driver IC, and discharges a solution containing protein filled in a pressurized chamber as a result of the elastic deformation of the diaphragm. A drive pulse generation circuit generates a drive voltage pulse and supplies this to the head chip in order to discharge a solution containing protein from the head chip. The drive current detection circuit detects a drive current flowing between the diaphragm and separate electrodes. Since the waveform of the detected drive current and the peak current value and so on differ in the case where the discharge status is normal and in the case where it is abnormal, a defective discharge can be discriminated by detecting such change.
机译:提出了一种能够可靠地将生物样品固定在固相上的分配技术。头芯片基于从头驱动器IC输出的驱动控制信号在膜片和单独的电极之间施加电压脉冲,并且由于膜片的弹性变形而排出填充在加压室内的包含蛋白质的溶液。驱动脉冲产生电路产生驱动电压脉冲并将其提供给头芯片,以便从头芯片排出包含蛋白质的溶液。驱动电流检测电路检测在膜片和分开的电极之间流动的驱动电流。由于在放电状态正常的情况下和异常的情况下,检测到的驱动电流的波形和峰值电流值等的波形不同,因此通过检测该变化,能够判别放电不良。

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