Sensitivity Prediction Method, Apoptosis Induction Methods, Mammalian Dysfunction Treatment Method, Sensitivity Prediction Method, and Colon or Colorectal Cancer Treatment Method in Mammals

摘要

SENSITIVITY PREDICTION METHOD, APOPTOSIS INDUCTION METHODS, MAMMAL DIFFUSION TREATMENT METHOD, COLONET CANCER EXAMINATION METHOD AND EXAMINATION TESTING METHODS AND METHODS or more biomarkers in mammalian cell and tissue samples. According to the tests and methods described, detection of expression of one or more of these biomarkers predicts or indicates that the sample of cells or tissue will be sensitive to apoptosis-inducing agents such as Apo2L / TRAIL. Or anti-DR5 antagonist antibodies. Certain biomarkers that can be examined include fucosyltransferases, particularly fucosyltransferase 3 (FUT3) and / or fucosyltransferase 6 (FUT6), as well as sialyl Lewis A and / or X antigens. Kits and industrialized articles are also provided.