首页> 外国专利> Compounds derived from pirimido - 4,5 - B - oxazines; Preparation procedure; Pharmaceutical composition comprising Said compound and use of the compound in the treatment of diabetes mellitus and / or obesity.

Compounds derived from pirimido - 4,5 - B - oxazines; Preparation procedure; Pharmaceutical composition comprising Said compound and use of the compound in the treatment of diabetes mellitus and / or obesity.

机译:衍生自pirimido-[4,5-B]-恶嗪的化合物;准备程序;包含所述化合物的药物组合物以及所述化合物在治疗糖尿病和/或肥胖症中的用途。

摘要

Compounds of formula (I) or salts thereof, wherein A, and R1 to R5 are as defined in the specification, are DGAT-1 inhibitors and are thereby useful in the treatment of, for example, obesity. Processes to make compounds of formula (I) are also described.
机译:其中A和R 1至R 5如说明书中所定义的式(I)化合物或其盐是DGAT-1抑制剂,因此可用于治疗例如肥胖症。还描述了制备式(I)化合物的方法。

著录项

  • 公开/公告号CL2006003672A1

    专利类型

  • 公开/公告日2008-02-08

    原文格式PDF

  • 申请/专利权人 ASTRAZENECA AB;

    申请/专利号CL20060003672

  • 发明设计人 BIRCH ALAN MARTIN;KEMMITT PAUL DAVID.;

    申请日2006-12-21

  • 分类号A61K31/5383;A61P3/00;C07D239/00;C07D265/28;C07D498/04;

  • 国家 CL

  • 入库时间 2022-08-21 20:08:34

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