首页> 外国专利> Polypeptide comprising a precursor protein of insulin-like growth factor, IGF - 1 Human,In which the Peptide cleavage by a protease and is reduced through the modification of the precursor protein and its use for T

Polypeptide comprising a precursor protein of insulin-like growth factor, IGF - 1 Human,In which the Peptide cleavage by a protease and is reduced through the modification of the precursor protein and its use for T

机译:包含胰岛素样生长因子IGF-1人前体蛋白的多肽,其中该肽被蛋白酶切割并通过修饰该前体蛋白及其在T中的用途而被还原

摘要

The invention relates to stabilized polypeptides having an IGF-1 or IGF-2 sequence and an E-peptide sequence, where the natural physiological cleavage of the E-peptide from the IGF is prevented.
机译:本发明涉及具有IGF-1或IGF-2序列和E-肽序列的稳定化的多肽,其中防止了从IGF自然裂解E-肽。

著录项

  • 公开/公告号CL2007001614A1

    专利类型

  • 公开/公告日2008-08-08

    原文格式PDF

  • 申请/专利权人 NOVARTIS AG;

    申请/专利号CL20070001614

  • 发明设计人 GLASS;DAVID JONATHAN Y FORNARO;MARA.;

    申请日2007-06-06

  • 分类号A61K38/30;C07K14/65;

  • 国家 CL

  • 入库时间 2022-08-21 20:08:36

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