首页> 外国专利> S-nitrosothiol Compounds; Synthesis; Intermediate Compounds, Pharmaceutical Composition and use in the treatment of diseases mediated by nitric oxide such asHypertension, thrombosis, among others.

S-nitrosothiol Compounds; Synthesis; Intermediate Compounds, Pharmaceutical Composition and use in the treatment of diseases mediated by nitric oxide such asHypertension, thrombosis, among others.

机译:S-亚硝基硫醇化合物;合成;中间体化合物,药物组合物,以及用于治疗由一氧化氮介导的疾病(例如高血压,血栓形成等)的用途。

摘要

The present invention relates to stable S-nitrosothiols derivatives of formula (I) having vasodilating effect and which inhibit the aggregation of the platelets and which therefore are useful for the preparation of medicaments for treatment of NO related diseases. The invention also relates to a process for the synthesis of the compounds of formula (I) and to intermediate compounds thereof.
机译:本发明涉及式(I)的稳定的S-亚硝基硫醇衍生物具有血管舒张作用并抑制血小板聚集,因此可用于制备治疗NO相关疾病的药物。本发明还涉及式(I)化合物的合成方法及其中间体化合物。

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