Use of compound capable of antagonizing at least partially oncogenic activity, viral vector containing nucleic acid sequence coding for such a compound and pharmaceutical composition in which the compound is comprised

摘要

The present invention relates to the use of a compound capable of antagonizing at least partially the oncogenic activity of the protein Mdm2 for the preparation of a pharmaceutical composition intended more particularly to a treatment of cancers with no p53 context. It further relates to a viral vector comprising a nucleic acid sequence coding for a compound capable of inhibiting at least partially the oncogenic activity of the protein Mdm2, and to a pharmaceutical composition intended for treating cancers in connection with the p53 context and containing a compound capable of inhibiting the oncogenic activity of the protein Mdm2.