首页> 外国专利> Three - 5-azerbaijani-1-ylcomonyl pyrazin-2-yl oxy - 1-methylethoxy - n-1h-pyrazol-3-ylebenzamida, containing components, preparation process and Application

Three - 5-azerbaijani-1-ylcomonyl pyrazin-2-yl oxy - 1-methylethoxy - n-1h-pyrazol-3-ylebenzamida, containing components, preparation process and Application

机译:三[5-(5-氮杂双亚甲-1-基共酰基)吡嗪-2-基]氧基-[1-甲基乙氧基] -n-1h-吡唑-3-基苯甲酰胺,含有组分,制备方法和应用

摘要

A Novel Crystalline form of 3 - [5 - (azetidin - 1 - 2 - il - orazom ilcarbonil) oxy] - 5 - [(1-methylethyl) oxy] - N - 1H pyrazole - 3 - ilbenzamida as described in the specification.This Compound is a glucokinase Activator (GQ) and is useful as a Pharmaceutical Agent in the Treatment or prevention of a disease or medical condition mediated by GQ, which generates a Lower Threshold glucosico for Insulin Secretion.It also describes procedures for the manufacture of Crystal form, Pharmaceutical compositions containing the Crystalline form, and the use of Crystalline form in the medical treatment.
机译:如说明书中所述,新的晶体形式为3- [5-(氮杂环丁烷-1-2-il-奥拉唑咪唑)氧基] -5-((1-甲基乙基)氧基] N-1H吡唑-3-ilbenzamida。该化合物是葡萄糖激酶激活剂(GQ),可用作治疗或预防GQ介导的疾病或医学状况的药物,GQ会产生下阈值的葡萄糖苷以分泌胰岛素,还描述了制造晶体的程序。形式,含有结晶形式的药物组合物,以及该结晶形式在医疗中的用途。

著录项

  • 公开/公告号UY30822A1

    专利类型

  • 公开/公告日2008-07-31

    原文格式PDF

  • 申请/专利权人 ASTRAZENECA AB;

    申请/专利号UY20070030822

  • 发明设计人 GARY PETER TOMKINSON;JAMES MCCABE;

    申请日2007-12-20

  • 分类号A61P7/12;C07D205;C07D229;C07D241;C07D403;

  • 国家 UY

  • 入库时间 2022-08-21 20:05:55

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