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COMBINATIONS COMPRISING AT LEAST ONE DIRECT THROMBIN INHIBITOR FOR THE TREATMENT OF THROMBOSIS

机译:包含至少一种直接凝血酶抑制剂的组合治疗血栓形成

摘要

The present invention relates to novel pharmaceutical compositions comprising at least one direct thrombin inhibitor and at least one additional active compound selected from the groups consisting of platelet inhibitors, low molecular weight heparins (LMWH) and heparinoids as well as unfractionated heparin, factor XSUBa /SUBinhibitors, combined thrombin/factor XSUBa /SUBinhibitors, fibrinogen receptor antagonists (glycolprotein IIb/IIa antagonists) and Vitamin K antagonists, optionally together with one or more pharmaceutically acceptable excipients or carriers for the treatment of thrombosis.
机译:本发明涉及新颖的药物组合物,其包含至少一种直接凝血酶抑制剂和至少一种选自血小板抑制剂,低分子量肝素(LMWH)和类肝素以及未分级肝素,X <SUB的活性化合物。 > a 抑制剂,凝血酶/ X因子X a 抑制剂,纤维蛋白原受体拮抗剂(糖蛋白IIb / IIa拮抗剂)和维生素K拮抗剂,以及一种或多种药学上可接受的赋形剂或载体血栓形成的治疗。

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