首页> 外国专利> Methyltransferses derived from plants methyltransferase genes methods for preparing the same and process for producing ermanin 57-dihydroxy-34'-dimethylflavone in microorganism by using the same

Methyltransferses derived from plants methyltransferase genes methods for preparing the same and process for producing ermanin 57-dihydroxy-34'-dimethylflavone in microorganism by using the same

机译:植物甲基转移酶基因衍生的甲基转移及其制备方法和在微生物中产生曼黄素57-二羟基-34'-二甲基黄酮的方法

摘要

The invention of the methyl transferase derived from plants (o-methyltransferases), their genes and the methyl the recombinant expression vector to produce the transformed microorganism transferase and the method for manufacturing a methyl transferase using the same and to a method for producing a multi-methylation (multiple methylation) of metabolites using the same. ; than More particularly, the present invention is rice and each is a selective separation of different methyl transferase from soybean, their genes, the methyl transferase gene to the expression vector containing one or more, in which the transformed E. coli, using the same methyl-transferase in the production process and the non-IRMA methyl transferase (ermanin; 5,7-dihydroxy-3,4-dimethylflavone) Using Multiple microbial expression relates to a method of mass production, the methyl transferase according to the present invention The chemical synthesis method is useful, but more easily mass produced at low cost through a very difficult metabolic biotransformation reaction product can be widely used because a new drug development.
机译:发明一种源自植物的甲基转移酶(o-甲基转移酶),它们的基因和甲基,用于产生转化的微生物转移酶的重组表达载体,以及使用该重组表达载体生产甲基转移酶的方法,以及一种生产多代谢物的甲基化(多重甲基化)。 ;尤其是,本发明是水稻,每个都是从大豆,其基因,甲基转移酶基因到含有一个或多个表达载体的表达载体中选择性分离不同的甲基转移酶,其中转化的大肠杆菌使用相同的甲基-微生物生产中的α-转移酶和非IRMA甲基转移酶(ermanin; 5,7-二羟基-3,4-二甲基黄酮)使用多种微生物表达涉及大量生产的方法,根据本发明的甲基转移酶合成方法是有用的,但是由于新药的开发,通过非常困难的代谢生物转化反应产物更容易以低成本大量生产。

著录项

  • 公开/公告号KR100782084B1

    专利类型

  • 公开/公告日2007-12-04

    原文格式PDF

  • 申请/专利权人 건국대학교 산학협력단;

    申请/专利号KR20060037830

  • 发明设计人 안중훈;김정호;김봉규;

    申请日2006-04-26

  • 分类号C12N15/54;C12N9/10;

  • 国家 KR

  • 入库时间 2022-08-21 19:54:32

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