A method of predicting METASTATIC Serous Ovarian Cancer

摘要

method u043fu0440u043eu0433u043du043eu0437u0438u0440u043eu0432u0430u043du0438u00a0 u043cu0435u0442u0430u0441u0442u0430u0437u0438u0440u043eu0432u0430u043du0438u00a0 u0441u0435u0440u043eu0437u043du043eu0433u043e cancer u00a0u0438u0447u043du0438u043au043eu0432, u0437u0430u043au043bu044eu0447u0430u044eu0449u0438u0439u0441u00a0 in evaluation of some parameters and predicting the ability of tumor to be u0438u0442u0438u00a0 mets cancer u0437u0430u0431u043eu043bu0435u0432u0430u043du0438u00a0, u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0, u043eu0446u0435u043du0438u0432u0430u044eu0442u0441u00a0 only morphological parameters of the tumor and u0432u0435u0440u043eu00a0u0442u043du043eu0441u0442u044c u0440u0430u0437u0432u0438u0442u0438u00a0 mets definitions u0434u0435u043bu00a0u044eu0442 on formulas;where x1 is the intensity of the u043cu0435u0447u0435u043du0438u00a0 receptors for progesterone (score), the absence of the expression of progesterone receptors in tumor cells is 0 points; u044du043au0441u043fu0440u0435u0441u0441u0438u00a0 receptors progesterone u0432u044bu00a0u0432u043bu0435u043du0430 in 1 to 10% of cells - 1 point; progesterone receptor u0432u0438u0437u0443u0430u043bu0438u0437u0438u0440u0443u0435u0442u0441u00a0 11 - 50% tumor cells - 2 points; progesterone receptor u043eu043fu0440u0435u0434u0435u043bu00a0u044eu0442u0441u00a0 51 - 100% u0440u0430u043au043eu0432u044b x cells - 3 points;;h2 is the expression PCNA (u00a0u0434u0435u0440u043du043eu0433u043e antigen u043fu0440u043eu043bu0438u0444u0435u0440u0438u0440u0443u044eu0449u0438u0445 cells (%), u043eu043fu0440u0435u0434u0435u043bu00a0u0435u0442u0441u00a0 of PCNA - positive cells in the tumor.;the x3 - mitotic index (), u043eu043fu0440u0435u0434u0435u043bu00a0u0435u0442u0441u00a0 by counting the total number of figures u0434u0435u043bu0435u043du0438u00a0 per 1000 tumor cells.;u04454 - u0443u0434u0435u043bu044cu043du0430u00a0 u0434u043eu043bu00a0 square spontaneous u043du0435u043au0440u043eu0437u043eu0432 (%) u0438u0437u043cu0435u0440u00a0u0435u0442u0441u00a0 through u043cu043eu0440u0444u043eu043cu0435u0442u0440u0438u0447u0435u0441u043au0438u0445 nets or one television u0438u0437u043eu0431u0440u0430u0436u0435u043du0438u00a0%, with u043au043eu043du0435u0447u043du0430u00a0 p u0435u0440u0435u043cu0435u043du043du0430u00a0 y can take u0437u043du0430u0447u0435u043du0438u00a0 ranging from 0 to 1, u0437u043du0430u0447u0435u043du0438u00a0 0Y0,5 should be regarded as an indicator of the low risk of cancer u043cu0435u0442u0430u0441u0442u0430u0437u0438u0440u043eu0432u0430u043du0438u00a0 u0441u0435u0440u043eu0437u043du043eu0433u043e u00a0u0438u0447u043du0438u043au043eu0432, in the u0432u0440u0435u043cu00a0 as 0.5Y1 suggests the high u0432u0435u0440u043eu00a0u0442u043du043eu0441u0442u0438 u043cu0435u0442u0430u0441u0442u0430u0437u0438u0440u043eu0432u0430u043du0438u00a0.