首页> 外国专利> DIARYL-UREA SUBSTANCES WITH CHINESE-INHIBITING EFFECT

DIARYL-UREA SUBSTANCES WITH CHINESE-INHIBITING EFFECT

机译:具有中国抑制作用的尿素类物质

摘要

The present invention provides methods of using aryl ureas to treat diseases and conditions associated with signal transduction pathways comprising at least one of raf, VEGFR, PDGFR, p38 and/or FLT-3. The present invention also provides compositions and methods for identifying conditions and diseases which can be modulated with compounds of the present invention. These methods facilitate the selection of subjects who can be efficiently treated with compounds of the present invention. Additionally, the invention provides methods for monitoring subjects who have been administered a compound of the present invention.
机译:本发明提供了使用芳基脲来治疗与包括raf,VEGFR,PDGFR,p38和/或FLT-3中的至少一种的信号转导途径有关的疾病和病症的方法。本发明还提供了鉴定可被本发明化合物调节的状况和疾病的组合物和方法。这些方法有助于选择可以用本发明的化合物有效治疗的受试者。另外,本发明提供了用于监测已经施用了本发明化合物的受试者的方法。

著录项

  • 公开/公告号DE602004011340T2

    专利类型

  • 公开/公告日2008-11-06

    原文格式PDF

  • 申请/专利权人 BAYER HEALTHCARE LLC;

    申请/专利号DE20046011340T

  • 发明设计人

    申请日2004-05-19

  • 分类号G01N33/574;

  • 国家 DE

  • 入库时间 2022-08-21 19:48:15

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