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DRUG SCREENING AND MOLECULAR DIAGNOSTIC TEST FOR EARLY DETECTION OF COLORECTAL CANCER, REAGENTS, AND METHODS THEREOF

机译:早期筛查大肠癌的药物筛查和分子诊断试验,试剂及方法

摘要

PPROBLEM TO BE SOLVED: To provide a new approach to the early detection of colorectal cancer (CRC). PSOLUTION: The method for screening the drug comprises the step of acquiring the quantified level data of the cDNA on a predetermined polynucleotide and by using at least one multivariate statistical analysis, comparing the level of cDNA originating from a tissue of a patient with a cDNA originating from a control tissue sample, a program including a command to provide the result of the analysis or a machine-readable medium in which the program is stored, and selecting at least one of biological model systems for such as cancers, for example CRC, lung, prostate, and breast, and neurodegenerative diseases, for example Alzheimer's and ALS, and selecting at least one drug for screening the system, selecting at least two biomarkers, and the step of administering at least one drug to the prescribed system and the step of monitoring the response of the biomarkers. PCOPYRIGHT: (C)2009,JPO&INPIT
机译:

要解决的问题:为早期检测结直肠癌(CRC)提供一种新方法。

解决方案:筛选药物的方法包括以下步骤:获取预定多核苷酸上cDNA的定量水平数据,并使用至少一种多变量统计分析,将来自患者组织的cDNA水平与源自对照组织样品的cDNA,包括提供分析结果的命令的程序或存储该程序的机器可读介质,并为例如癌症选择生物学模型系统中的至少一种CRC,肺,前列腺,乳腺和神经退行性疾病,例如阿尔茨海默氏病和ALS,并选择至少一种药物来筛选系统,选择至少两种生物标记物以及向处方系统施用至少一种药物的步骤,监测生物标志物反应的步骤。

版权:(C)2009,日本特许厅&INPIT

著录项

  • 公开/公告号JP2009060908A

    专利类型

  • 公开/公告日2009-03-26

    原文格式PDF

  • 申请/专利权人 INTELLIGENESCAN INC;

    申请/专利号JP20080243636

  • 发明设计人 LEE NANCY M;

    申请日2008-09-24

  • 分类号C12Q1/68;G01N33/574;G01N33/50;G01N33/15;C12M1/00;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 19:44:41

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