Total Synthesis Method for Pradienolide B and Pradienolide D

摘要

A compound represented by formula (12) (wherein P7 represents a hydrogen atom or a hydroxyl-protecting group; R1 represents a hydrogen atom or a hydroxyl group), and formula (13) (wherein P1 represents a hydrogen atom) Or a protective group for a hydroxyl group; P8 means a protective group for a hydrogen atom, acetyl group or hydroxyl group; P9 means a protective group for a hydrogen atom or hydroxyl group; (Wherein R5 represents a phenyl group which may have a halogen atom) may be formed in the presence of a catalyst. A method for producing a compound represented by formula (11), wherein P1, P7, P8, P9 and R1 have the same meanings as defined above.