Method for evaluating compound using molecule on Rb pathway as index and method for molecular diagnosis

摘要

The present invention provides a molecule that is present on the Rb pathway and can be used as a drug discovery target or tumor marker for an anticancer agent, and a method that enables evaluation of a compound (anticancer agent candidate compound) using the molecule. For the purpose. IL-8, IL-8 receptor, ECT2, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, CCNE2, FEN1, HMGB2, CENPE, KIF20A, CDC25C, CDCA8, KIF11, HCAP-E, HCAP-G, KTTC2, The object can be achieved by a method for evaluating a compound that detects the interaction between the HCAP-C, BUB1, NEK2, CCNA2, or KIF18A gene or protein and the test compound.