首页> 外国专利> PREVENTIVE OR THERAPEUTIC AGENT FOR CEREBRAL ISCHEMIC INJURY OR CEREBRAL ISCHEMIA REPERFUSION IN STROKE

PREVENTIVE OR THERAPEUTIC AGENT FOR CEREBRAL ISCHEMIC INJURY OR CEREBRAL ISCHEMIA REPERFUSION IN STROKE

机译:脑卒中脑缺血性损伤或脑缺血再灌注的预防或治疗剂

摘要

The present invention provides a preventive or therapeutic agent for cerebral ischemic injury or cerebral ischemic reperfusion injury in stroke such as cerebral infarction and cerebral hemorrhage which exerts its effect through a different mechanism from that of conventional therapeutic agents and can be taken for along period. The present invention is a preventive or therapeutic agent for cerebral ischemic injury or cerebral ischemic reperfusion injury in stroke which contains 6-fluoro-2′,5′-dioxospiro[chroman-4,4′-imidazolidine]-2-carboxamide as an active ingredient. A particularly preferable compound is an optically resolved (2S,4S)-form of fidarestat.
机译:本发明提供了针对脑梗塞或脑出血等中风的脑缺血损伤或脑缺血再灌注损伤的预防或治疗剂,其通过与常规治疗剂不同的作用机理发挥作用,并且可以长期服用。本发明是含有6-氟-2',5'-二氧代螺并[chroman-4,4'-咪唑烷] -2-羧酰胺作为活性成分的中风的脑缺血或脑缺血再灌注损伤的预防或治疗剂。成分。特别优选的化合物是非达司他的旋光(2S,4S)形式。

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