Inhibiting Smad2/3 signaling promotes neurite outgrowth in dorsal root ganglia

摘要

Regeneration of a lesioned CNS axon of a mature neuron, determined to be subject to regeneration inhibition by Smad2/3 signaling, is promoted by contacting the neuron with an inhibitor of Smad2/3 signaling sufficient to promote regeneration of the axon.