首页> 外国专利> European chip of chromosome and ('y-european chip') and procedure for the genotypping of y-snps (single nucleotide polymorphisms) that determine the most frequent haplogruphs in europe through dna chips. (Machine-translation by Google Translate, not legally binding)

European chip of chromosome and ('y-european chip') and procedure for the genotypping of y-snps (single nucleotide polymorphisms) that determine the most frequent haplogruphs in europe through dna chips. (Machine-translation by Google Translate, not legally binding)

机译:欧洲染色体和(“ y-欧洲芯片”)芯片以及y-snps(单核苷酸多态性)的基因分型方法,可通过dna芯片确定欧洲最常见的抄写。 (通过Google翻译进行机器翻译,没有法律约束力)

摘要

European y chromosome chip ("y-european chip") and procedure for the genotyping of y-snps (single nucleotide polymorphisms) that determine the most frequent haplogroups in europe using dna chips. The procedure is based on the amplification of the fragments containing the snps of interest and the determination of the base involved in the polymorphism by means of a mini-sequencing reaction using primers that carry a tail (tag) at its 5 'end, for later detection by hybridizing the products of the mini-sequencing reaction with a microarray consisting of sequences complementary to the tails (ctag). (Machine-translation by Google Translate, not legally binding)
机译:欧洲y染色体芯片(“ y-欧洲芯片”)和y-snps(单核苷酸多态性)的基因分型方法,可确定使用dna芯片在欧洲最常见的单倍群。该程序基于扩增含有目标氨基酸的片段,并通过微测序反应确定多态性所涉及的碱基,该反应采用在5'末端带有尾部(标签)的引物进行小规模测序,之后进行通过将微型测序反应的产物与由与尾巴(ctag)互补的序列组成的微阵列杂交来进行检测。 (通过Google翻译进行机器翻译,没有法律约束力)

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