SPECTROSCOPY MEASUREMENTS OF THE CONCENTRATION OF A SUBSTANCE IN A SCATTERING TISSUE

摘要

A method and device (1) for calculating the concentration of glucose in skin (12) are described, wherein the skin (12) is illuminated by polarized NIR light (5) provided by a NIR source (2) and a polarizer (3) and a absorbance spectrum of the skin is detected by passing backscattered light (6) through an analyzer (7) to a spectrometer (8). The device may further comprises patches (9,10) for stretching the skin in a stretching direction (11). By measuring a first absorbance spectrum with the skin being in a first, unstreched state and a second absorbance spectrum with the skin being in a second, stretched state the contribution of collagen to the absorbance spectrum may be determined and a corresponding correction may be applied in the calculation of the glucose concentration.