A BIOMARKER AND SCREENING METHOD OF DRUG HAVING TERATOGENICITY AND SIDE EFFECTS USING THEREOF

摘要

The present invention relates to a biomarker for searching for teratogenicity and side effect-inducing drugs and a search method using the same. Specifically, a biomarker for increasing or decreasing gene expression in common to various teratogenicity-causing drugs and a method for searching for teratogenicity and side effects-inducing drug using the same. It is about. The biomarker of the present invention can be usefully used to monitor and determine drugs or chemicals having a risk of new teratogenicity and side effects by using reaction genes selected through a DNA microarray chip as a biomarker, and a mechanism of action that causes teratogenicity. It can be used as a tool to identify.;Teratogenicity drug, microarray