首页> 外国专利> RNA BINDING PROTEIN NAPOR-3 INHIBITED BY ETHANOL IN PRENATAL RAT BRAIN

RNA BINDING PROTEIN NAPOR-3 INHIBITED BY ETHANOL IN PRENATAL RAT BRAIN

机译:乙醇可抑制大鼠前脑组织RNA结合蛋白NAPOR-3的表达

摘要

A RNA binding protein Napor-3 gene of which expression is suppressed in a brain of fetal rat is provided to identify the act of ethanol which suppresses the gene expression at the stage of developing a nervous tissue of fetal rat. A RNA binding protein Napor-3 gene is transcribed to mRNA of the sequence number 1 and the gene expression is suppressed by ethanol in a brain of fetal rat. The expression of domain comprising 4561th~4645th nucleotide of Napor-3 gene mRNA and mRNA domain having 95% homology with the domain having the nucleotides is inhibited by ethanol. The brain of fetal rat is a mesencephalon, hindbrain, and hippocampus.
机译:提供了在胎鼠脑中表达被抑制的RNA结合蛋白Napor-3基因,以鉴定乙醇在胎鼠神经组织发育阶段抑制基因表达的作用。 RNA结合蛋白Napor-3基因被转录为序列号1的mRNA,并且该基因的表达被乙醇抑制在胎鼠脑中。乙醇抑制了Napor-3基因mRNA的第4561〜4645位核苷酸的结构域和与具有该核苷酸的结构域具有95%同源性的mRNA结构域的表达。胎鼠的大脑是中脑,后脑和海马。

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