USE OF A CORTICOSTEROID IN COMBINATION WITH DIURETIC AND ANTACID FOR THE TREATMENT OF VASCULAR STENOSIS AND PREVENTION OF VASCULAR RESTENOSIS

摘要

1. The use of at least one corticosteroid in combination with at least one diuretic and at least one antacid for the manufacture of a medicament for the treatment of atherosclerotic vascular stenosis and for preventing vascular restenosis after angioplasty. The use according to claim 1, characterized in that the aforementioned corticosteroid is selected from the group consisting of prednisone, prednisolone, methylprednisolone, cortisone, hydrocortisone, betamethasone, dexamethasone, triamcinolone, parametasone and their salts. The use according to claim 1 or 2, characterized in that the aforementioned corticosteroid is prednisone. The use according to claim 1, characterized in that the above diuretic is selected from the group consisting of furosemide, bumetanide, ethacrylic acid, torsemide, chlortalidone, hydrochlorothiazide, hydroflumetazide and metazolone. The use according to claim 1 or 4, characterized in that the aforementioned diuretic is furosemide. The use according to claim 1, characterized in that the above antacid is selected from the group consisting of omeprazole, pantoprazole, esomeprazole, ilaprazole, lanzoprazole, rabeprazole, cimetidine, ranitidine, famotidine and nizatidine. The use according to claim 1 or 6, characterized in that the above antacid is omeprazole. The use according to any one of claims 1 and 2, 4 or 6, characterized in that the above corticosteroid is administered in an amount of from 2 to 150 mg per day. The use according to claim 3, characterized in that the above prednisone is administered in an amount of from 25 to 100 mg per day. The use according to any one of claims 1 and 2, 4, 6 or 9, characterized in that the above diuretic is introduced into