INACTIVATED VACCINE AGAINST PORCINE TRANSMISSIBLE GASTROENTERITIS (PTGE) AND PORCINE EPIDEMIC DIARRHEA (PED) FROM ENTERIC VIRUS OF ARTIFICIALLY INFECTED COLOSTRUM-FREE PIGS (PTGE/PED VACCINE)

摘要

FIELD: veterinary science.;SUBSTANCE: invention relates to virology. The invention can be used at industrial hog farms. The vaccine contains a mix of inactivated porcine transmissible gastroenteritis and epidemic diarrhea viruses and adjuvant. Viruses are obtained from the small bowel of artificially infected colostrum-free pigs where such viruses accumulate in a titer of 6.7-7.5 lg ID₅₀/ml and show an antigenic activity of at least 1:8 in EIA. Virus suspensions are mixed at a 1:1 ratio by volume with 20% of aluminium hydrate added to the mix as adjuvant.;EFFECT: vaccine PTGE/PED is harmless and non-reactogenic and has a pronounced protective effect.;3 tbl, 6 ex