首页> 外国专利> Medicament useful for suppressing the immune system, treating necrotic cell death, ischemia, hypoxia, trauma, diabetes mellitus, myocardial infarction and/or cerebral ischemia, and treating the patients after resustication

Medicament useful for suppressing the immune system, treating necrotic cell death, ischemia, hypoxia, trauma, diabetes mellitus, myocardial infarction and/or cerebral ischemia, and treating the patients after resustication

机译:用于抑制免疫系统,治疗坏死细胞死亡,局部缺血,缺氧,外伤,糖尿病,心肌梗塞和/或脑缺血以及在复苏后治疗患者的药物

摘要

Medicament for suppressing the immune system and for treating the patient having a disease of necrotic cell death, is claimed. Independent claims are included for: (1) a targeted suppression of the biosynthesis of individual proteins, comprising applying ribo-oligonucleotides and/or small-interfering ribonucleic acids, where the diseases are presented with a defective localization of endogenous proteins; and (2) a targeted suppression of the biosynthesis of insulin, comprising applying ribo-oligonucleotides or small-interfering ribonucleic acids to the patients having diabetes mellitus. ACTIVITY : Immunosuppressive; Vasotropic; Vulnerary; Antidiabetic; Cardiant; Cerebroprotective. MECHANISM OF ACTION : TAP protein inhibitor.
机译:要求保护用于抑制免疫系统和治疗患有坏死性细胞死亡疾病的患者的药物。包括以下独立权利要求:(1)靶向抑制单个蛋白质的生物合成,包括施加核糖寡核苷酸和/或小干扰核糖核酸,其中所述疾病表现为内源蛋白质定位缺陷。 (2)靶向抑制胰岛素的生物合成,包括对患有糖尿病的患者施用核糖寡核苷酸或小干扰核糖核酸。活动:免疫抑制;变压性伤药;抗糖尿病卡迪恩脑保护。作用机理:TAP蛋白抑制剂。

著录项

  • 公开/公告号DE102008053348A1

    专利类型

  • 公开/公告日2009-06-04

    原文格式PDF

  • 申请/专利权人 ARNETH BORROS M.;

    申请/专利号DE20081053348

  • 发明设计人 ARNETH BORROS M.;

    申请日2008-10-27

  • 分类号A61K45;A61P37/06;

  • 国家 DE

  • 入库时间 2022-08-21 19:09:01

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