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Transporters organic anions of the placenta and its gene
Transporters organic anions of the placenta and its gene
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机译:胎盘转运蛋白及其基因的有机阴离子
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摘要
A novel organic anion transporter gene participating in organic anion transportation in the placenta; and an organic anion transporter which is a polypeptide encoded by the gene. A placental organic anion transporter OAT4, more particularly, a placental organic anion transporter OAT4 having the amino acid sequence represented by SEQ ID NO:2 or an amino acid sequence derived therefrom by deletion, substitution or addition of a part of the amino acids thereof. A nucleic acid (preferably DNA) having a base sequence encoding the placental organic anion transporter OAT4 or a base sequence hybridizable therewith under stringent conditions.
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机译:一个新的有机阴离子转运蛋白基因,参与胎盘中的有机阴离子转运;有机阴离子转运蛋白,是该基因编码的多肽。胎盘有机阴离子转运蛋白OAT4,更具体地讲,是指具有氨基酸序列SEQ ID NO:2所示的胎盘有机阴离子转运蛋白OAT4或通过缺失,取代或添加一部分氨基酸而衍生自其的氨基酸序列。具有在严格条件下编码胎盘有机阴离子转运蛋白OAT4的碱基序列或可与其杂交的碱基序列的核酸(优选DNA)。
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