NOVEL PHOSPHINE-BORANE COMPOUND, METHOD FOR PRODUCING THE SAME AND METHOD FOR PRODUCING HYDROGEN-PHOSPHINE-BORANE COMPOUND

摘要

PROBLEM TO BE SOLVED: To provide an optically active phosphine-borane compound which is useful for the production of an optically active phosphine ligand and allows easy production of any antipode and a method for producing the compound.;SOLUTION: The phosphine-borane compound is represented by formula (P-1) (wherein R¹ and R² are each hydrogen, a hydrocarbon group or a substituted hydrocarbon group and may be selected so as to or not to cause asymmetry on the phosphorus by the presence of these groups and R³ is an asymmetric hydrocarbon group or a substituted asymmetric hydrocarbon group). The method for producing the phosphine-borane compound comprises subjecting a hydrogen-phosphine-borane compound represented by formula (P-2) (wherein R¹ and R² are the same as defined above) and an optically active isocyanate compound represented by formula (3) (wherein R³ is the same as defined above) to coupling reaction.;COPYRIGHT: (C)2010,JPO&INPIT