Synthesis of 8-{1- (3,5-bis- (trifluoromethyl) phenyl) -ethoxy} methyl -8-phenyl-1,7-diaza-spiro 4.5 decan-2-one compounds Methods and intermediates for

摘要

This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations.