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The hydrophobic licorice extract content constituent which

机译:疏水性甘草提取物含量成分

摘要

PROBLEM TO BE SOLVED: To obtain the subject stable radix extract composition having good handleability and useful for providing a preparation having high stability by including a polyhydric alcohol fatty acid ester, a hydrophobic Glycyrrhizae Radix extract and oil and fat. SOLUTION: This composition comprises (A) a polyhydric alcohol fatty acid ester (preferably a diglycerol monofatty acid ester such as diglyceryl monoisostearate, especially having =7.5 HLB), (B) a hydrophobic Glycyrrhizae Radix extract and (C) oil and fat (preferably exhibiting fluidity at ordinary temperature, e.g. a dialkyl carbonate). The component B is obtained by subjecting an extracted solution obtained by extracting root or rhizome of Glycyrrhiza glabra with an organic solvent such as ethanol or an extract obtained by removing the solvent to purification treatment such as decoloring or deodorization. The composition contains glabridin, glabrene, or the like, as main ingredient. The composition comprises 10-50 wt.% component A, 1-20 wt.% component B and the balance of the component C.
机译:要解决的问题:为了获得具有良好的可操作性的主题稳定的基根提取物组合物,通过包含多元醇脂肪酸酯,疏水性的甘草基提取物和油脂,可用于提供具有高稳定性的制剂。溶液:该组合物包含(A)多元醇脂肪酸酯(最好是二甘油单脂肪酸酯,例如单异硬脂酸二甘油酯,尤其是HLB≤7.5),(B)疏水性甘草提取物和(C)油脂优选在常温下表现出流动性,例如碳酸二烷基酯。成分B是通过对甘草的根或根茎提取的提取液用乙醇等有机溶剂或将溶剂除去后的提取液进行脱色或脱臭等纯化处理而得到的。该组合物包含加拉巴丁,降冰片烯等作为主要成分。该组合物包含10-50重量%的组分A,1-20重量%的组分B和其余的组分C。

著录项

  • 公开/公告号JP4418550B2

    专利类型

  • 公开/公告日2010-02-17

    原文格式PDF

  • 申请/专利权人 丸善製薬株式会社;

    申请/专利号JP19990038681

  • 申请日1999-02-17

  • 分类号A61K36/48;A61K8/97;A61K9/06;A61K47/14;A61K47/44;A61P17/00;A61Q1/00;A61Q19/00;

  • 国家 JP

  • 入库时间 2022-08-21 18:59:15

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