Aqueous dispersions suitable for the production of binders or coatings for solid oral dosage forms, use of the aqueous dispersions and redispersible powders

摘要

An aqueous dispersion for the production of binders or coatings for solid oral drugs having a water content of 90-40 wt. % and a solids portion of 10-60 wt. %, whereby said solids portion is composed of:(A) 10-99 wt. % of a polymer mixture consisting of:(a) 75-99 wt. % of a polymethacrylate copolymer consisting of up to 98-85 wt. % of alkyl (meth)acrylate monomers with C1-C4 alkyl residues and up to 2-15 wt. % of alkyl (meth)acrylate monomers with a quaternary ammonium group in the alkyl residue, and (b) 25-1 wt. % of an alkali salt of carboxymethylcellulose having a weight average molecular weight of less than 150,000, and(B) 90-1 wt. % of at least one substance normally added to pharmaceutical formulations.