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Kit compound having a structure derived from mononucleoside or mononucleotide, nucleic acids, labeling substance, and nucleic acid detection method

机译:具有衍生自单核苷或单核苷酸的结构的试剂盒化合物,核酸,标记物质和核酸检测方法

摘要

For example, to provide a labeling substance detectable effectively double helix structure of nucleic acids. A compound having a structure derived from mononucleoside or mononucleotide, the structure is the following formula (1), compounds represented by (1b), or (1c), or a stereoisomer, tautomer or the I provide the salts thereof. For example, B is an atomic group having a nucleobase skeleton, E is an atomic group having a peptoid structure or peptide structure or atomic group having a structure derived from any of them deoxyribose backbone, ribose or backbone, It is, respectively, is an atomic group that exhibits fluorescence hydrogen atom or a protecting group,, Z 12 and Z 11 may be the same or different. None [Selection Figure]
机译:例如,提供一种可有效检测核酸双螺旋结构的标记物质。具有衍生自单核苷或单核苷酸的结构的化合物,该结构为下式(1),由(1b)或(1c)表示的化合物,或立体异构体,互变异构体或I,提供其盐。例如,B是具有核碱基骨架的原子团,E是具有拟肽结构或肽结构的原子团或具有衍生自脱氧核糖主链,核糖或主链中的任一个的结构的原子团。具有荧光氢原子或保护基的原子团Z 12 和Z 11 可以相同或不同。无[选择图]

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