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Co-administration of cG250 and IL-2 or IFN-α for treating cancer such as renal cell carcinomas
Co-administration of cG250 and IL-2 or IFN-α for treating cancer such as renal cell carcinomas
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机译:cG250与IL-2或IFN-α的共同给药可用于治疗癌症,例如肾细胞癌
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摘要
A method for enhancing the therapeutic effect of cytokine treatment is disclosed. More specifically the present invention relates to a method for administering to a tumor patient a therapeutic dose of cytokine in combination with antibodies directed against the tumor associated antigen carbonic anhydrase IX (CAIX/G250/MN). The improved treatment method is characterized in a significantly reduced cytokine-related toxicity combined with potentiated effectiveness of anti-G250 antibody alone, resulting in a positive therapeutic response with respect to that observed with single anti-tumor agents alone.
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