Listeria monocytogenes cytotoxin Listeriolysin S

摘要

The invention relates to a gene derivable from the LIPI-3 pathogenicity island of the gram positive pathogen Listeria monocytogenes and to the Listeria monocytogenes cytotoxin, Listeriolysin S. The present invention further relates to the appllication of Listeriolsyin S as a target for diagnostic screening and as a therapeutic agent such as an anti-cancer agent.