tag ), for later detection by hybridizing the products of the mini-sequencing reaction with a microarray consisting of the sequences complementary to the tails ( cTag )."/> EUROPEAN CHROMOSOME CHIP AND ('Y-EUROPEAN CHIP') AND PROCEDURE FOR THE GENOTIPATE OF Y-SNPS (SINGLE NUCLEOTIDE POLYMORPHISMS) THAT DETERMINE THE MOST FREQUENT HOPLOGRUPES IN EUROPE THROUGH DNA CHIPS.
首页> 外国专利> EUROPEAN CHROMOSOME CHIP AND ('Y-EUROPEAN CHIP') AND PROCEDURE FOR THE GENOTIPATE OF Y-SNPS (SINGLE NUCLEOTIDE POLYMORPHISMS) THAT DETERMINE THE MOST FREQUENT HOPLOGRUPES IN EUROPE THROUGH DNA CHIPS.

EUROPEAN CHROMOSOME CHIP AND ('Y-EUROPEAN CHIP') AND PROCEDURE FOR THE GENOTIPATE OF Y-SNPS (SINGLE NUCLEOTIDE POLYMORPHISMS) THAT DETERMINE THE MOST FREQUENT HOPLOGRUPES IN EUROPE THROUGH DNA CHIPS.

机译:欧洲染色体芯片和(“ Y-欧洲芯片”)以及通过DNA芯片确定欧洲最常见的H-LOGP的Y-SNPS(单核苷酸多态性)基因组的程序。

摘要

European Y chromosome chip ("Y-European Chip") and procedure for the genotyping of Y-SNPs (Single Nucleotide Polymorphisms) that determine the most frequent haplogroups in Europe using DNA chips. The procedure is based on the amplification of the fragments that contain the SNPs of interest and the determination of the base involved in the polymorphism by means of a mini-sequencing reaction using primers that at their 5 'end carry a tail ( tag ), for later detection by hybridizing the products of the mini-sequencing reaction with a microarray consisting of the sequences complementary to the tails ( cTag ).
机译:欧洲Y染色体芯片(“ Y-欧洲芯片”)和Y-SNP(单核苷酸多态性)的基因分型方法,可确定使用DNA芯片在欧洲最常见的单倍群。该程序基于扩增包含目标SNP的片段并通过使用5'端带有尾巴的引物(标签)通过微测序反应确定涉及多态性的碱基),以便稍后通过将微测序反应的产物与微阵列(由与尾巴互补的序列( cTag )组成)杂交来进行检测。

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