NEW DIMERS DERIVED FROM BILIARY ACIDS FUNCTIONED IN POSITION 3 OF RING A. METHOD FOR SYNTHESIS AND APPLICATIONS.

摘要

New dimers derived from bile acidsfunctionalized at position 3 of ring A. Method forsynthesis and applications The new compounds result from theconjugation of 3β-derived amino stereosidesof natural bile acids (colic, deoxycholic,ursodeoxycholic, chenodeoxycholic and lithocolic) with formsactivated from bridges 1 to 10 of Table 1. Acidsresulting are obtained by three new general methods ofsynthesis and are grouped in Tables 2 to 6. All claims are claimed.acids I-i-H, II-iH, III-i H, IV-i-H andV-i-H, the methods of obtaining itand its applications as surfactants. They also claim thesodium and potassium salts of the above acids and specificallythe compounds identified by the codesI-i-Na, II-i Na,III-i Na, IV-i-Na andVineyard;I-i-K, II-i K,III-i K, IV-i-K andV-i-K, the methods of obtainingsalts and applications as surfactants thereof. Inall abbreviated formulas i vary from 1 to 10corresponding with the bridges of union.