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AGONISTS AND ANTAGONISTS OF GUANYLATE CYCLASE RECEPTORS OF THE GRUENEBERG GANGLION FOR USE IN MODULATING ANIMAL BEHAVIOUR
AGONISTS AND ANTAGONISTS OF GUANYLATE CYCLASE RECEPTORS OF THE GRUENEBERG GANGLION FOR USE IN MODULATING ANIMAL BEHAVIOUR
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机译:用于调节动物行为的格吕内堡神经节的瓜纳石酸环化受体的激动剂和拮抗剂
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摘要
The present invention relates to physical and pharmaceutical methods of increasing or decreasing the activity of the Grueneberg Ganglion (GG) in a subject. In one embodiment, the method comprising administering a compound to the GG, wherein the compound is an agonist or antagonist, respectively, for at least one guanylyl cyclase receptor or the receptor's downstream effectors. The present invention also relates to methods of screening candidate compounds for their ability to modulate the activity of the GG. The present invention also relates to methods and kits for positively identifying a GG neuron based upon the presence or absence of the pGC- G or pGC-A receptors.
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