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METHOD FOR DIAGNOSIS OF POST-OPERATIVE RECURRENCE IN PATIENTS WITH HEPATOCELLULAR CARCINOMA

机译:诊断肝细胞癌患者术后复发的方法

摘要

Provided are a method of diagnosing the recurrence or possibility of recurrence of hepa¬ tocellular carcinoma after hepatocellular carcinoma surgery and a method of screening a drug for preventing the recurrence of hepatocellular carcinoma after hepatocellular carcinoma surgery and treating hepatocellular carcinoma. Specifically, the recurrence or possibility of recurrence of hepatocellular carcinoma after hepatocellular carcinoma surgery is diagnosed and a drug for preventing the recurrence of hepatocellular carcinoma after surgery and treating hepatocellular carcinoma is screened, by measuring expression levels of a metastatic tumor antigen 1 or metastasis associated 1 (MTAl) protein in a biological sample taken from a patient in which hep¬ atocellular carcinoma recurs or is likely to recur after hepatocellular carcinoma surgery and comparing the measured expression levels of the MTAl protein with those of a normal control group.
机译:提供了诊断肝细胞癌手术后肝细胞癌复发或复发的方法,以及筛选用于预防肝细胞癌手术后肝癌复发和治疗肝细胞癌的药物的方法。具体地,通过测量转移性肿瘤抗原1的表达水平或转移相关的1,诊断出肝细胞癌手术后肝细胞癌的复发或复发的可能性,并筛选出用于预防手术后肝细胞癌复发和治疗肝细胞癌的药物。取自肝细胞癌术后复发或可能复发的患者的生物学样品中的(MTA1)蛋白,并将测得的MTA1蛋白表达水平与正常对照组进行比较。

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