Immunological analytical device for the determination of advanced glycosylation end products (AGEs)

摘要

The invention provides an immunological analytical method, reagents and devices for determination the glycosylated protein, e.g., the advance glycosylation end products (AGEs), comprising reagents for determining the glycosylated protein, which comprises a displaying carrier suspension and the antigen or antibody immobilized on the surface of the displaying carrier; and a test strip, comprising of: a base plate, and constitutive parts provided on said base plate, said constitutive parts consisting of a water absorption pad for the sample, a porous fiber membrane, a displaying carrier fiber block and at least one immobilized substance. The immunological reaction of the glycosylated protein antigen or anti-glycosylated protein antibody can be determined based on the agglutination phenomenon or accompanied changes of absorbance or color and the presence or absence of the AGEs in the diabetic patient can be known accordingly such that the practitioner can be prevent the occurrence of the complicated condition, or block further the progression of the complicated conditions.