Assay for determination of heparin based on factor Xa using a heparin-modifying component

摘要

Heparin-dependent inactivation of admixed factor Xa is quantified. Before addition of factor Xa, the sample is incubated with a heparin-modifying component. The sample may be incubated with an enzyme from the group of heparinases or with an enzyme from the group of glucuronidases or with a mixture of different enzymes from one or both of these groups. An independent claim is included for a test kit for carrying out the method.