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NONLINEAR SPECTROSCOPIC METHODS FOR IDENTIFYING AND CHARACTERIZING MOLECULAR INTERACTIONS
NONLINEAR SPECTROSCOPIC METHODS FOR IDENTIFYING AND CHARACTERIZING MOLECULAR INTERACTIONS
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机译:非线性光谱学方法用于分子相互作用的鉴定和表征
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摘要
This invention provides methods and devices for identifying and/or characterizing interactions involving molecules, including, but not limited to, identifying and/or characterizing interactions involving target molecules and candidate molecules. The present invention provides methods using multidimensional infrared spectrographic techniques, such as four wave mixing and pump - probe techniques, for identifying interactions involving biomolecules and therapeutic candidate molecules, and for characterizing such interactions in terms of their binding coefficients and/or equilibrium constants.
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