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DIAGNOSIS, PROGNOSIS AND MONITORING OF DISEASE PROGRESSION OF SYSTEMIC LUPUS ERYTHEMATOSUS THROUGH BLOOD LEUKOCYTE MICROARRAY ANALYSIS
DIAGNOSIS, PROGNOSIS AND MONITORING OF DISEASE PROGRESSION OF SYSTEMIC LUPUS ERYTHEMATOSUS THROUGH BLOOD LEUKOCYTE MICROARRAY ANALYSIS
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机译:通过血液白细胞微阵列分析诊断系统性红斑狼疮的疾病进展的诊断,预后和监测
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摘要
The present invention includes an apparatus, system and method for the development and use of transcriptional modules by obtaining individual gene expression levels from cells obtained from one or more patients with a disease or condition; recording the expression value for each gene in a table that is divided into clusters; iteratively selecting gene expression values for one or more transcriptional modules by: selecting for the module the genes from each cluster that match in every disease or condition; removing the selected genes from the analysis; and repeating the process of gene expression value selection for genes that cluster in a sub-fraction of the diseases or conditions; and iteratively repeating the generation of modules.
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