A MEDICAMENT COMPRISING A PARASYMPATHETIC AGONIST AND A SYMPATHETIC ANTAGONIST OR A SYMPATHETIC AGONIST

摘要

A medicament for topical administration to a human or animal eye comprises at least two pharmacologically active agents. One of the active agents is a parasympathetic agonist, such as pilocarpine, and the other active agent is either a sympathetic antagonist such as dapiprazole or thymoxamine, or a sympathetic agonist such as brimonidine or iopidine. The medicament is preferably in the form of a liquid composition, such as eye drops, or a gel or ointment and may comprise a slow-release composition. The medicament acts to improve visual acuity for a period of several hours, and may be beneficial in cases of presbyopia, myopia, hypermetropia, astigmatism and/or impaired night vision.