COMPOSITION FOR CAUSING DRUG TOXICITY CAUSED BY CYTOCHROME P450 3A4(CYP3A4)

摘要

PURPOSE: A composition containing BI-1 protein is provided to enhance activity of cytochrome p450 3A4(CYP3A4) and reduce drug toxicity.;CONSTITUTION: A pharmaceutical composition for reducing drug toxicity caused by activity reduction of cytochrome p450 3A4(CYP3A4) contains BI-1 protein as an active ingredient. The drug which causes toxicity by cytochrome p450 3A4(CYP3A4) activity reduction is clarithromycin, erythromycin, quinidine, alprazolam, and diazepam. A pharmaceutical composition for preventing and treating disorder caused by drug toxicity by cytochrome p450 3A4(CYP3A4) contains BI-1 protein as an active ingredient.;COPYRIGHT KIPO 2010