peptide decoys for the production of drugs, for the prevention or treatment of autoimmune diseases.problems associated with the occurrence of antibodies against exogenous proteins were related to intended

摘要

The use of peptidic and pseudopeptidic mimics of factor VIII (I) in medicines for the prevention and treatment of disorders due to the appearance of antibodies against endogenous or exogenous factor VIII or its derivatives, which may be recombinant or not, administered in cases of hemophilia A. The use of peptidic and pseudopeptidic mimics of factor VIII of formula (I) in medicines for the prevention and treatment of disorders due to the appearance of antibodies against endogenous or exogenous factor VIII or its derivatives, which may be recombinant or not, administered in cases of hemophilia A. (X1)n1-C-Xa-C-(X2)n2 (I) n1, n2 = 0 or 1; X1, X2 = an amino acid that may be natural or not; and Xa = a chain of 8 - 10 amino acids that may be natural or not. Independent claims are also included for the peptide sequences themselves.