The present invention relates to a method is not - invasive of the collection of biological data useful for the establishment of a diagnosis or prognosis of a cutaneous pathology, in particular, in a patient, characterized in that: a) a sample is taken of the skin, containing the biological material, for application to said patient's skin of an adhesive layer, followed by withdrawal of said adhesive, b) is detected by mass spectrometry are in the sample at least one protein whose presence in the absence or the variation of the quantity of concentration with respect to a standard value is associated with the presence, at the change or absence of a cutaneous pathology particulière.une such a method is particularly suitable for the establishment of a diagnostic or prognostic of psoriasis.
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