Being the analytical instrument in order to detect the target material or the analytical instrument which analyzes the analysis mannered, or these analytical instruments and

摘要

PROBLEM TO BE SOLVED: To detect a target substance with high contrast.;SOLUTION: In the analysis of a target substance using a light-transmitting substrate and a metal for inducing plasmon resonance, a low refractive index layer with an opening portion is used, which forms an interface with the substrate, and which has a lower refractive index than the substrate. Light emitted from a substrate side is totally reflected at the interface to irradiate the metal arranged in the opening portion with evanescent light. Light generated from the target substance by plasmon resonance of the evanescent light is detected. The radiation of evanescent light to a material other than the target substance can be reduced, and thereby light emission from the material other than the target substance, e.g., a molecule floating around the target substance, can be reduced.;COPYRIGHT: (C)2009,JPO&INPIT