Method for the prediction of the outcome of the treatment of human diseases using drugs metabolised by N acetyltransferase 2 human (NAT2) based on genetic polymorphisms

摘要

Method for the prediction of the outcome of treatment for diseases with drugs metabolized by human n acetyltransferase 2 human (NAT2) based on genetic polymorphisms, the present invention relates to the field of molecular biology and genu00e2mica, especially the farmacogenu00e2mi Ca.The invention describes the presence of new polymorphisms in the gene that encodes for the enzyme arilamina n acetyltransferase 2 human (NAT2), which is responsible for the metabolism of drugs in the therapy of several diseases of important miscellaneous etiologies, as well as many toxins. Carcinogens present in food, cigarette and in the environment.The present invention includes methodology capable of use in the therapy using polymorphisms described above.