compound, pharmaceutical composition, use of a compound, methods for treating a disease, and for producing a compound, engineered strain, and use of an engineered strain

摘要

COMPOUND, PHARMACEUTICAL COMPOSITION, USE OF A COMPOUND, METHODS FOR THE TREATMENT OF A DISEASE, AND FOR THE PRODUCTION OF A COMPOUND, ENGENITIRED CEPA, AND, USE OF AN ENGINEERED CEPA The present invention relates to analogues of 18,21- didesoximacbecin that are useful, p. eg in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, angiogenesis-dependent diseases, autoimmune diseases and / or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and / or prophylaxis of B-cell cancer or malignancies.