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COMPOSITION COMPRISING (±) - 2 - (DIMETHYLAMINO) METHYL) CYCLOHEXANE AND THE USE THEREOF FOR SYNTHESIS OF CIS OR TRANS (±) - 2 - ((DIMETHYLAMINO) METHYL)-1-(ARYL)CYCLOHEXANOL
COMPOSITION COMPRISING (±) - 2 - (DIMETHYLAMINO) METHYL) CYCLOHEXANE AND THE USE THEREOF FOR SYNTHESIS OF CIS OR TRANS (±) - 2 - ((DIMETHYLAMINO) METHYL)-1-(ARYL)CYCLOHEXANOL
Compositions comprising (±)-2-((dimethylamino)methyl)cyclohexanone, a transition-metal salt, and an organic solvent and methods of preparing (±)-cis-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols, in particular (±)-cis-2-((dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol, are disclosed herein. In one embodiment, the (±)-2-((dimethylamino)methyl)cyclohexanone and transition-metal salt are in the form of a (±)-2-((dimethylamino)methyl)cyclohexanone:transition-metal salt complex. In another embodimemt, aryl is 3-methoxyphenyl.
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