PLATINUM NANOPARTICLE LABEL MEDIATED DEPOSITION OF PLATINUM CATALYST FOR ULTRASENSITIVE ELECTROCHEMICAL IMMUNOSENSORS

摘要

PLATINUM NANOPARTICLE LABEL MEDIATED DEPOSITION OF PLATINUM CATALYST FOR ULTRASENSITIVE ELECTROCHEMICAL IMMUNOSENSORS ABSTRACTA method for providing an ultrasensitive electrochemical immunosensor, comprising using a platinum (Pt) enhancement process to grow Pt catalyst based on the principle of seed-mediated nucleation and growth; using target-selective probe molecule-conjugated Pt nanoparticle labels as seeds wherein the resulting Pt catalyst accelerates a hydrogen evolution reaction in a proton-rich electrolytemedium for signal amplification, thereby improving the sensitivity of the electrochemical immunosensor or biosensor.FIGURE 1